scOrange Blog

Author: Iva Černoša, May 10, 2019

Pinpointing Lineage Differentiation in Human Preimplantation Embryotic Cells

Combine clustering and time component to pinpoint the time of trophectoderm (TE) and inner cell mass (ICM) differentiation in human preimplantation embryotic cells and recreate a part of study by Petropoulos et al. (Cell, 2016)

Author: Iva Černoša, May 6, 2019

X And Y Chromosome Expression in Human Preimplantation Embryos

Using the single cell data from Petropoulos et al. (Cell, 2016) we determine the karyotype (XY, XX, X0) of the cells and inspect the time of activation of Y chromosome in a preimplantation embryo.